Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NCK1 | P16333 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1760730 | 0.84 | CYP1A2 (0.59) | CYP1A2CYP2A6KDM4ETDP1CCR1 | |
| SCHEMBL599041 | 0.81 | KDM4E (0.60) | CYP1A2CYP2A6KDM4ETDP1RAPGEF4 | |
| SCHEMBL598921 | 0.79 | CYP1A2 (0.52) | CYP1A2CYP2A6KDM4ETDP1RAPGEF4 | |
| SCHEMBL597802 | 0.79 | CYP1A2 (0.63) | CYP1A2CYP2A6TDP1ALDH1A1HPGD | |
| SCHEMBL27423499 | 0.79 | RAPGEF4 (0.39) | CYP1A2CYP2A6KDM4ETDP1RAPGEF4 | |
| SCHEMBL13316749 | 0.79 | TP53 (0.46) | CYP1A2CYP2A6KDM4ETDP1ALDH1A1 | |
| SCHEMBL28346830 | 0.76 | TUBB4A (0.44) | CYP1A2CYP2A6KDM4ETDP1ALDH1A1 | |
| SCHEMBL29659617 | 0.76 | TUBB4A (0.44) | CYP1A2CYP2A6KDM4ETDP1ALDH1A1 | |
| SCHEMBL29659608 | 0.75 | TUBB4A (0.46) | CYP1A2CYP2A6KDM4ETDP1ALDH1A1 | |
| SCHEMBL1760714 | 0.74 | CYP1A2 (0.61) | CYP1A2CYP2A6KDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080017496-A1 | SYSTEM, METHOD AND PROCESS OF RECOVERING OIL FROM USED AUTOMOBILE TIRES | THOMPSON DAVID B | 2008-01-24 | — | — | US | disclosed |