Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572112 | 0.86 | ALDH1A1 (0.56) | PKMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL15695046 | 0.85 | ALDH1A1 (0.58) | PKMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL572005 | 0.85 | ALDH1A1 (0.58) | PKMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL17296068 | 0.85 | ALDH1A1 (0.58) | PKMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL571017 | 0.85 | ALDH1A1 (0.58) | PKMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL571040 | 0.85 | ALDH1A1 (0.58) | PKMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL571607 | 0.85 | ALDH1A1 (0.58) | PKMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL571286 | 0.85 | ALDH1A1 (0.58) | PKMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL572045 | 0.85 | ALDH1A1 (0.58) | PKMMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL572109 | 0.85 | ALDH1A1 (0.58) | PKMMAPTALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014984-B1 | GLUCOSAMINE-PEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1982-12-01 | — | — | EP | disclosed |