Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15610987 | 0.79 | EGLN1 (0.57) | EGLN1POLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12502562 | 0.71 | EGLN1 (0.71) | EGLN1POLBACHEMAPK1ALDH1A1 | |
| Bicarbonate SCHEMBL25171118 | 0.69 | POLB (0.64) | POLBL3MBTL1S1PR2ALDH1A1TSHR | |
| SCHEMBL21195170 | 0.68 | KMT2A (0.48) | POLBALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL290791 | 0.68 | POLB (0.70) | POLBL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL10568031 | 0.67 | POLB (0.61) | EGLN1POLBL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12503126 | 0.65 | EGLN1 (1.00) | EGLN1 | |
| SCHEMBL18885299 | 0.65 | GSK3B (0.46) | EGLN1POLBACHEMAPK1ALDH1A1 | |
| SCHEMBL11729211 | 0.65 | HTR6 (0.48) | EGLN1POLBL3MBTL1MAPK1MEN1 | |
| SCHEMBL29880432 | 0.64 | POLB (1.00) | POLBL3MBTL1ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57131789-A | — | — | None | — | — | JP | disclosed |
| JP-S57131789-A | 1,7-NAPHTHYRIDINE DERIVATIVE | TAMURA YASUMITSU | 1982-08-14 | — | — | JP | disclosed |