SCHEMBL11221074

SCHEMBL11221074

O=[N+]([O-])c1ccc(N=Nc2ccc(O)c(Cl)c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.66
KMT2A Q03164 7/20 0.66
MAPT P10636 5/20 0.66
NPC1 O15118 4/20 0.66
RAB9A P51151 4/20 0.66
TDP1 Q9NUW8 3/20 0.66
NPSR1 Q6W5P4 3/20 0.66
MAPK1 P28482 3/20 0.66
HSP90AA1 P07900 2/20 0.66
RECQL P46063 1/20 0.66
ALDH1A1 P00352 6/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
PTGS2 P35354 2/20 0.60
PTGS1 P23219 1/20 0.60
POLB P06746 3/20 0.57
HTT P42858 2/20 0.57
LMNA P02545 2/20 0.57
GAA P10253 3/20 0.47
GLA P06280 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17502084 1.00 MEN1 (0.66) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL17502051 0.87 MEN1 (0.66) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL17502049 0.87 MEN1 (0.66) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL16285336 0.87 MEN1 (0.69) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL31681253 0.85 ALDH1A1 (0.69) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL2374057 0.85 ALDH1A1 (0.69) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL2374053 0.85 ALDH1A1 (0.69) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11209624 0.82 TDP1 (0.59) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL11209626 0.82 TDP1 (0.59) MEN1KMT2AMAPTNPC1RAB9A
SCHEMBL9488022 0.81 PTGS2 (0.57) MEN1KMT2AMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9268065-B1 Composition for polarizing film, polarizing film, and display device including the polarizing film SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-02-23 US disclosed
WO-1982001554-A1 POLYCARBONATES STABILIZED BY HALOHYDROCARBON,HALOCARBON OR SILANE GROUPS MCALISTER ROY E 1982-05-13 WO disclosed
EP-0027144-A4 POLYCARBONATES STABILIZED BY HALOHYDROCARBON, HALOCARBON OR SILANE GROUPS. MCALISTER ROY E 1981-05-19 EP disclosed
EP-0027144-A1 POLYCARBONATES STABILIZED BY HALOHYDROCARBON, HALOCARBON OR SILANE GROUPS McALISTER, Roy Edward (US) 1981-04-22 EP disclosed
WO-1980002290-A1 POLYCARBONATES STABILIZED BY HALOHYDROCARBON,HALOCARBON OR SILANE GROUPS MCALISTER R 1980-10-30 WO disclosed