Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.67 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.51 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.51 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22658027 | 0.95 | DGKA (0.65) | DGKALPAR3LPAR2DNM1PRSS1 | |
| SCHEMBL11318947 | 0.91 | DGKA (0.69) | DGKALPAR3LPAR2DNM1PAM | |
| SCHEMBL11316013 | 0.91 | DGKA (0.69) | DGKALPAR3LPAR2DNM1PAM | |
| SCHEMBL11329230 | 0.91 | DGKA (0.69) | DGKALPAR3LPAR2DNM1PAM | |
| SCHEMBL11315998 | 0.91 | DGKA (0.69) | DGKALPAR3LPAR2DNM1PAM | |
| SCHEMBL11318114 | 0.91 | DGKA (0.69) | DGKALPAR3LPAR2DNM1PAM | |
| SCHEMBL28437253 | 0.89 | DGKA (0.55) | DGKALPAR3LPAR2DNM1PRSS1 | |
| SCHEMBL11318096 | 0.88 | NAAA (0.58) | DGKALPAR3LPAR2DNM1PRSS1 | |
| SCHEMBL9642883 | 0.88 | NAAA (0.58) | DGKALPAR3LPAR2DNM1PRSS1 | |
| SCHEMBL11331413 | 0.88 | NAAA (0.58) | DGKALPAR3LPAR2DNM1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012351-B1 | PHOSPHONIC ACID ESTERS, THEIR PREPARATION, THEIR USE AS EMULSIFYING AND DISPERSING AGENTS, AND THEIR AQUEOUS COMPOSITIONS | BAYER AG (DE) | 1982-07-07 | — | — | EP | disclosed |
| US-4280960-A | Phosphonic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-28 | — | — | US | disclosed |
| EP-0012351-A1 | Phosphonic acid esters, their preparation, their use as emulsifying and dispersing agents, and their aqueous compositions | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |