Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099430 | 0.81 | MAPK1 (0.47) | POLBMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL27310045 | 0.75 | CA12 (0.39) | POLBMEN1KMT2ASMN1; SMN2SLC6A4 | |
| SCHEMBL733060 | 0.74 | MEN1 (0.47) | POLBMEN1KMT2AHTTSLC6A3 | |
| SCHEMBL18479 | 0.74 | CYP19A1 (0.52) | POLBMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL28038815 | 0.73 | KMT2A (0.38) | POLBMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL10332372 | 0.73 | TSHR (0.41) | POLBMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL561284 | 0.72 | HTT (0.64) | POLBMEN1KMT2AHTTSMN1; SMN2 | |
| Methyl 3,5-Dinitrobenzoate SCHEMBL418416 | 0.72 | SMN1; SMN2 (0.60) | POLBMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL7274798 | 0.70 | TSHR (0.50) | POLBMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL909296 | 0.70 | TSHR (0.45) | POLBMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340537-A | Monoazo dyes of the thiazole series having a heterocyclic substituent in the 4-position | BASF AKTIENGESELLSCHAFT (DE) | 1982-07-20 | — | — | US | disclosed |
| EP-0017769-B1 | DYESTUFFS OF THE THIAZOLE SERIES AND THEIR USE | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0017769-A1 | Dyestuffs of the thiazole series and their use | BASF Aktiengesellschaft (DE) | 1980-10-29 | — | — | EP | disclosed |