Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28038817 | 0.77 | ALDH1A1 (0.44) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL10385920 | 0.76 | KMT2A (0.44) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL4581245 | 0.75 | LMNA (0.59) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL9516997 | 0.75 | PKM (0.59) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL11099430 | 0.73 | MAPK1 (0.47) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL9463456 | 0.73 | KMT2A (0.49) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL11221464 | 0.73 | POLB (0.41) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL18479 | 0.70 | CYP19A1 (0.52) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL9513718 | 0.70 | NPC1 (0.52) | KMT2AMAPTLMNAMEN1HTT | |
| SCHEMBL28039099 | 0.69 | ALDH1A1 (0.46) | KMT2AMAPTLMNAMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105051004-A | Novel prodrugs and methods of use thereof | AUCKLAND UNISERVICES LTD | 2015-11-11 | — | — | CN | disclosed |