Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221700 | 1.00 | MAPK1 (0.50) | MAPK1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11217176 | 0.89 | TDP1 (0.49) | MAPK1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11217181 | 0.89 | TDP1 (0.49) | MAPK1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11229910 | 0.86 | ALDH1A1 (0.37) | MAPK1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11229907 | 0.86 | ALDH1A1 (0.37) | MAPK1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11220857 | 0.85 | ALDH1A1 (0.41) | MAPK1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11220860 | 0.85 | ALDH1A1 (0.41) | MAPK1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11538242 | 0.81 | MAPK1 (0.73) | MAPK1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11538240 | 0.81 | MAPK1 (0.73) | MAPK1ALDH1A1L3MBTL1TDP1MAPT | |
| SCHEMBL11187622 | 0.81 | MAPK1 (0.73) | MAPK1ALDH1A1L3MBTL1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334064-A | Cephalosporin vinyl halides | ELI LILLY AND COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4334063-A | Cephalosporin vinyl halides | ELI LILLY AND COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4299954-A | MICROBIOCIDES | ELI LILLY AND COMPANY (US) | 1981-11-10 | — | — | US | disclosed |