Formic Acid

Formic Acid

SCHEMBL11221746

O=CO.SN1CCOCC1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.36
CA1 P00915 2/20 0.36
CA9 Q16790 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 2/20 0.33
MMP1 P03956 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
CA2 P00918 1/20 0.32
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL79194 0.83
Fluoride SCHEMBL28867502 0.83 MGLL (0.42) CA12CA1CA9SMN1; SMN2CA7
Bicarbonate SCHEMBL11609855 0.81 HSD17B10 (0.44) CA12CA1CA9SMN1; SMN2CA7
Formic Acid SCHEMBL27691390 0.80
Formic Acid SCHEMBL17076608 0.76 SMN1; SMN2 (0.42) CA12CA1CA9SMN1; SMN2CA7
Formic Acid SCHEMBL4305037 0.74 SMN1; SMN2 (0.41) CA12CA1CA9SMN1; SMN2CA7
Formic Acid SCHEMBL17969575 0.74 RECQL (0.37) CA12CA1CA9SMN1; SMN2CA7
Dioxane SCHEMBL10454709 0.73
SCHEMBL15386448 0.72
SCHEMBL21538586 0.70 MGLL (0.33) CA12CA7CA14MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4343339-A DIENE POLYMERS WITH REACTIVE GROUPS BAYER AKTIENGESELLSCHAFT (DE) 1982-08-10 US disclosed