⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL28867502 | 1.00 | MGLL (0.42) | — | |
| SCHEMBL15386448 | 0.87 | — | — | |
| SCHEMBL28071004 | 0.85 | MGLL (0.33) | — | |
| SCHEMBL21538586 | 0.85 | MGLL (0.33) | — | |
| Bicarbonate SCHEMBL11609855 | 0.85 | HSD17B10 (0.44) | — | |
| Formic Acid SCHEMBL11221746 | 0.83 | CA12 (0.36) | — | |
| Methane SCHEMBL11749753 | 0.79 | CA12 (0.39) | — | |
| Methane SCHEMBL11748578 | 0.79 | CA12 (0.39) | — | |
| SCHEMBL23436477 | 0.73 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL21669920 | 0.70 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 964 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023036289-A1 | HYDROXAMIC ACID COMPOUND HAVING ENPP1 INHIBITORY ACTIVITY AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2023-03-16 | — | — | WO | claimed |
| EP-3894402-A1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. Hoffmann-La Roche AG (CH) | 2021-10-20 | — | — | EP | claimed |
| EP-3681884-A1 | RAD51 INHIBITORS | Cyteir Therapeutics, Inc. (US) | 2020-07-22 | — | — | EP | claimed |
| US-20200222364-A1 | CARBAZOLE DERIVATIVES FOR THE TREATMENT OF FIBROTIC DISEASES AND RELATED SYMPTOMS, AND CONDITIONS THEREOF | RAZIEL THERAPEUTICS LTD. (IL) | 2020-07-16 | — | — | US | claimed |
| WO-2020120528-A1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2020-06-18 | — | — | WO | claimed |
| US-10632102-B2 | Carbazole derivatives for the treatment of fibrotic diseases and related symptoms, and conditions thereof | RAZIEL THERAPEUTICS LTD (IL) | 2020-04-28 | — | — | US | claimed |
| CN-106700140-B | Improve rubber composition and the application of rubber ageing-resistant performance | 北京彤程创展科技有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-109937042-A | Backbone-modified morpholino oligonucleotides and chimeras synthesized using phosphoramidite chemistry | 科罗拉多州立大学董事会法人团体 | 2019-06-25 | — | — | CN | claimed |
| CN-109836634-A | Rubber composition and vulcanized rubber and its preparation method and application | 中国石油化工股份有限公司 | 2019-06-04 | — | — | CN | claimed |
| CN-106032417-B | Rubber composition and vulcanized rubber and its application | 中国石油化工股份有限公司 | 2019-03-26 | — | — | CN | claimed |
| EP-0237955-A2 | Quinolonecarboxylic acid derivatives and their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | claimed |
| EP-0219446-A1 | Process for the preparation of N-tetrathiodimorpholine | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1987-04-22 | — | — | EP | claimed |
| CN-86101611-A | N7Process for the preparation of amidino-substituted mitomycin C derivatives | — | 1986-12-17 | — | — | CN | claimed |
| US-4614819-A | REACTING A THIOL ESTER COMPOUND WITH 7-AMINOCEPHALOSPORIN IN PRESENCE OF BORON TRIFLUORIDE | TOYAMA CHEMICAL CO., LTD. (JP) | 1986-09-30 | — | — | US | claimed |
| US-4550162-A | Process for the manufacture of enol derivatives | CIBA-GEIGY CORPORATION (US) | 1985-10-29 | — | — | US | claimed |
| US-4434287-A | Cephalosporin derivatives | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | claimed |
| US-4319027-A | Process for the manufacture of ceohem enol derivatives | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | claimed |
| US-4293462-A | Process for the manufacture of enol derivatives, and intermediates | CIBA-GEIGY CORPORATION (US) | 1981-10-06 | — | — | US | claimed |
| US-4110533-A | PROCESS FOR THE MANUFACTURE OF ENOL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-08-29 | — | — | US | claimed |
| US-4002594-A | THIOMORPHOLINE | PPG INDUSTRIES, INC. (US) | 1977-01-11 | — | — | US | claimed |