Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 20/20 | 0.71 |
| ▸ | NOS3 | P29474 | 19/20 | 0.71 |
| ▸ | NOS2 | P35228 | 7/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121986 | 0.84 | NOS3 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL1122129 | 0.83 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL1122204 | 0.81 | NOS1 (0.46) | NOS1NOS3NOS2 | |
| SCHEMBL1122359 | 0.80 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL1122333 | 0.79 | NOS3 (1.00) | NOS1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL1122254 | 0.77 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL1122399 | 0.77 | NOS1 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL2262987 | 0.72 | NOS1 (0.98) | NOS1NOS3NOS2 | |
| SCHEMBL1122051 | 0.72 | NOS3 (1.00) | NOS1NOS3NOS2 | |
| SCHEMBL2936290 | 0.71 | NOS1 (0.75) | NOS1NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883451-B9 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON INC (CA) | 2011-02-09 | — | — | EP | claimed |
| EP-1883451-B1 | SUBSTITUTED INDOLE COMPOUNDS HAVING NOS INHIBITORY ACTIVITY | NEURAXON INC (CA) | 2010-11-24 | — | — | EP | claimed |