SCHEMBL11222158

SCHEMBL11222158

O=C1c2ccccc2C(=O)c2c1ccc(Oc1ccccc1)c2S(=O)(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.62
MAPT P10636 8/20 0.47
KMT2A Q03164 7/20 0.47
MEN1 O00255 6/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 4/20 0.44
POLB P06746 5/20 0.44
MAPK1 P28482 4/20 0.44
LMNA P02545 3/20 0.44
HKDC1 Q2TB90 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
TP53 P04637 1/20 0.44
XBP1 P17861 1/20 0.44
HTT P42858 1/20 0.44
KCNA3 P22001 1/20 0.43
DAPK1 P53355 2/20 0.42
ALDH1A1 P00352 5/20 0.41
RECQL P46063 3/20 0.41
KDM4E B2RXH2 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30030177 0.80 ADORA2A (0.68) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL9861717 0.78 ADORA2A (0.69) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL11303111 0.77 ADORA2A (0.68) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL27727186 0.76 DAPK1 (0.47) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL11226616 0.76 PGAM1 (0.54) ADORA2AMAPTKMT2AMEN1POLB
SCHEMBL1764840 0.76 ADORA2A (0.66) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL159669 0.76 PGAM1 (0.56) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL29643579 0.76 PGAM1 (0.56) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL11231093 0.76 MAPT (0.46) ADORA2AMAPTKMT2AMEN1SMN1; SMN2
SCHEMBL5246506 0.74 PGAM1 (0.54) ADORA2AMAPTKMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4342700-A SALTS OF SUBSTITUTED ANTHRAQUINONESULFONIC ACID MITSUI TOATSU CHEMICALS, INC. (JP) 1982-08-03 US disclosed
US-4276187-A SALT OF AN ANTHRAQUINONESULFONIC ACID AND SODIUM METAVANADATE MITSUI TOATSU CHEMICALS INCORPORATED (JP) 1981-06-30 US disclosed