SCHEMBL30030177

SCHEMBL30030177

O=C1c2ccccc2C(=O)c2c1ccc(Oc1ccccc1)c2O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.68
MAPT P10636 10/20 0.67
KMT2A Q03164 7/20 0.67
MEN1 O00255 6/20 0.67
NPC1 O15118 3/20 0.67
RAB9A P51151 3/20 0.67
SMN1; SMN2 Q16637 5/20 0.57
ALDH1A1 P00352 5/20 0.57
MCL1 Q07820 3/20 0.57
MAPK1 P28482 3/20 0.57
BCL2 P10415 2/20 0.57
RECQL P46063 2/20 0.57
KDM4E B2RXH2 2/20 0.57
MAOA P21397 2/20 0.57
CYP3A4 P08684 1/20 0.57
HPGD P15428 1/20 0.57
ALOX15 P16050 1/20 0.57
ALOX12 P18054 1/20 0.57
APEX1 P27695 1/20 0.57
DAPK1 P53355 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22909076 0.83 MAPT (0.57) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL9861717 0.82 ADORA2A (0.69) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL11303111 0.81 ADORA2A (0.68) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL11222158 0.80 ADORA2A (0.62) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL29929605 0.80 MAPT (1.00) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL1426486 0.80 MAPT (1.00) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL31441205 0.80 MAPT (1.00) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL1764840 0.80 ADORA2A (0.66) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL11601411 0.79 MAPT (0.60) ADORA2AMAPTKMT2AMEN1NPC1
SCHEMBL11167387 0.79 ADORA2A (0.61) ADORA2AMAPTKMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220339910-A1 LAMINATED GLASS INTERLAYER FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2022-10-27 US disclosed