Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1715045 | 0.87 | CASP3 (0.34) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL101440 | 0.84 | CASP3 (0.35) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL10111280 | 0.81 | NPSR1 (0.33) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL872507 | 0.80 | CASP3 (0.36) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL3790860 | 0.80 | CASP3 (0.36) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL3340797 | 0.79 | APEX1 (0.40) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL101535 | 0.77 | CASP3 (0.32) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL14048649 | 0.77 | APEX1 (0.39) | NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7846770 | 0.77 | NPSR1 (0.35) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL11225554 | 0.76 | HTR1B (0.39) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314058-A | Indolins styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4147862-A | Method of preparing styryl-like compounds | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-04-03 | — | — | US | disclosed |
| US-4139274-A | Apparatus for changing color | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1979-02-13 | — | — | US | disclosed |