Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222608 | 0.87 | CASP3 (0.37) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL1714142 | 0.83 | HDAC3 (0.40) | NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10111280 | 0.83 | NPSR1 (0.33) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL14048649 | 0.81 | APEX1 (0.39) | NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29478248 | 0.80 | CASP3 (0.32) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL24584317 | 0.80 | PTGS2 (0.38) | RAB9ATDP1KDM4EALDH1A1LMNA | |
| SCHEMBL3340797 | 0.79 | APEX1 (0.40) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL101440 | 0.79 | CASP3 (0.35) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL101535 | 0.78 | CASP3 (0.32) | CASP3RAB9AATMNPSR1SENP8 | |
| SCHEMBL9885228 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230332210-A1 | REPORTER AND USE THEREOF | SFC CO., LTD. (KR) | 2023-10-19 | — | — | US | disclosed |
| US-20230332210-A1 | REPORTER AND USE THEREOF | SFC CO., LTD. (KR) | 2023-10-19 | — | — | US | disclosed |
| WO-2022139292-A1 | REPORTER AND USES THEREOF | 에스에프씨 주식회사 | 2022-06-30 | — | — | WO | disclosed |
| US-8044203-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044203-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| US-8044203-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2011-10-25 | — | — | US | disclosed |
| EP-1525265-B1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | UNIV CARNEGIE MELLON (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-1525265-B1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | UNIV CARNEGIE MELLON (US) | 2011-07-20 | — | — | EP | disclosed |
| EP-2258776-A1 | Fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2010-12-08 | — | — | EP | disclosed |
| EP-2258776-A1 | Fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2010-12-08 | — | — | EP | disclosed |
| US-20100267008-A1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2010-10-21 | — | — | US | disclosed |
| US-20100267008-A1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2010-10-21 | — | — | US | disclosed |
| US-20100267008-A1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2010-10-21 | — | — | US | disclosed |
| US-7615646-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-10 | — | — | US | disclosed |
| US-7615646-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-10 | — | — | US | disclosed |
| US-7615646-B2 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | CARNEGIE MELLON UNIVERSITY (US) | 2009-11-10 | — | — | US | disclosed |
| US-20060051758-A1 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-03-09 | — | — | US | disclosed |
| EP-1525265-A4 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | UNIV CARNEGIE MELLON (US) | 2005-06-22 | — | — | EP | disclosed |
| EP-1525265-A2 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE-MELLON UNIVERSITY (US) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004039894-A2 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | CARNEGIE MELLON UNIVERSITY (US) | 2004-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060051758-A1 | Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups | IDO1, TDO2, IDO2 | CASP3 536/4885RAB9A 2051/4885ATM 3357/4885 |
| US-20100267008-A1 | CHIRAL INDOLE INTERMEDIATES AND THEIR FLUORESCENT CYANINE DYES CONTAINING FUNCTIONAL GROUPS | IDO1, IDO2, INMT | CASP3 244/4885RAB9A 2698/4885ATM 4075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.