Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199902 | 0.79 | SMN1; SMN2 (0.42) | POLBKMT2ASMN1; SMN2HSD17B10PDE5A | |
| SCHEMBL10942993 | 0.77 | L3MBTL1 (0.44) | POLBKMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10944246 | 0.77 | L3MBTL1 (0.44) | POLBKMT2AL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL10944369 | 0.76 | SMN1; SMN2 (0.45) | POLBKMT2AL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL10942665 | 0.76 | SMN1; SMN2 (0.45) | POLBKMT2AL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL10942943 | 0.76 | L3MBTL1 (0.43) | POLBKMT2AL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL10944724 | 0.72 | SMN1; SMN2 (0.42) | POLBKMT2AL3MBTL1SMN1; SMN2HSD17B10 | |
| SCHEMBL11199916 | 0.70 | SMN1; SMN2 (0.44) | POLBKMT2AL3MBTL1SMN1; SMN2PDE5A | |
| SCHEMBL81066 | 0.69 | FFAR1 (0.66) | KMT2AFFAR1L3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8871859 | 0.69 | FFAR1 (0.66) | KMT2AFFAR1L3MBTL1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57106658-A | — | — | None | — | — | JP | disclosed |
| JP-S57106658-A | CARBOXYLIC ACID DERIVATIVE | SANTEN PHARMACEUT CO LTD | 1982-07-02 | — | — | JP | disclosed |