Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222806 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPTHTTLMNA | |
| SCHEMBL1639309 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1MAPTHTTLMNA | |
| SCHEMBL11223718 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPTHTTLMNA | |
| SCHEMBL11223676 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPTHTTLMNA | |
| SCHEMBL57738 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPTHTTMEN1 | |
| SCHEMBL57737 | 0.80 | ALDH1A1 (0.58) | ALDH1A1TDP1MAPTHTTMEN1 | |
| SCHEMBL3758839 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL48360 | 0.75 | GPR35 (0.53) | ALDH1A1TDP1MAPTHTTMEN1 | |
| SCHEMBL15926782 | 0.75 | TDP1 (0.70) | ALDH1A1TDP1MEN1KMT2ANPC1 | |
| SCHEMBL48361 | 0.75 | GPR35 (0.53) | ALDH1A1TDP1MAPTHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363905-A | PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4316981-A | Polycarbonate transesterification | GENERAL ELECTRIC COMPANY (US) | 1982-02-23 | — | — | US | disclosed |