Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296005 | 0.79 | TDP1 (0.53) | TDP1GAAALDH1A1GPR35MEN1 | |
| SCHEMBL28256635 | 0.79 | TDP1 (0.53) | TDP1GAAALDH1A1GPR35MEN1 | |
| SCHEMBL2475315 | 0.79 | GAA (0.66) | TDP1GAAALDH1A1GPR35TSHR | |
| SCHEMBL28294148 | 0.79 | TDP1 (0.53) | TDP1GAAALDH1A1GPR35MEN1 | |
| SCHEMBL23926472 | 0.78 | TDP1 (0.48) | TDP1GAAALDH1A1GPR35NPC1 | |
| SCHEMBL15910820 | 0.77 | TDP1 (0.47) | TDP1GAAALDH1A1GPR35MEN1 | |
| SCHEMBL10673736 | 0.76 | TDP1 (0.50) | TDP1GAAALDH1A1GPR35MEN1 | |
| SCHEMBL28910275 | 0.76 | TDP1 (0.50) | TDP1GAAALDH1A1GPR35MEN1 | |
| SCHEMBL14658363 | 0.76 | MET (0.47) | TDP1GAAALDH1A1GPR35HSP90AA1 | |
| SCHEMBL3690450 | 0.75 | GAA (0.49) | TDP1GAAALDH1A1GPR35MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57142968-A | — | — | None | — | — | JP | disclosed |
| JP-57142969-A | — | — | None | — | — | JP | disclosed |
| US-7371264-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-05-13 | — | — | US | disclosed |
| JP-S57142968-A | PREPARATION OF 4-HYDROXYINDOLE DERIVATIVE | NISSAN CHEM IND LTD | 1982-09-03 | — | — | JP | disclosed |
| JP-S57142969-A | SUBSTITUTED INDOLE | NISSAN CHEM IND LTD | 1982-09-03 | — | — | JP | disclosed |