Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2475315 | 0.79 | GAA (0.66) | TDP1GAAALDH1A1GPR35POLB | |
| SCHEMBL11223006 | 0.79 | TDP1 (0.53) | TDP1GAAALDH1A1GPR35POLB | |
| SCHEMBL28256635 | 0.79 | TDP1 (0.53) | TDP1GAAALDH1A1GPR35POLB | |
| SCHEMBL28296005 | 0.79 | TDP1 (0.53) | TDP1GAAALDH1A1GPR35POLB | |
| SCHEMBL28910275 | 0.76 | TDP1 (0.50) | TDP1GAAALDH1A1GPR35POLB | |
| SCHEMBL3822066 | 0.76 | GAA (0.47) | TDP1GAAALDH1A1GPR35POLB | |
| SCHEMBL23926472 | 0.75 | TDP1 (0.48) | TDP1GAAALDH1A1GPR35HSP90AA1 | |
| SCHEMBL12896239 | 0.75 | GAA (0.49) | TDP1GAAALDH1A1GPR35POLB | |
| SCHEMBL6626162 | 0.75 | GAA (0.49) | TDP1GAAALDH1A1GPR35POLB | |
| SCHEMBL18683061 | 0.75 | TDP1 (0.48) | TDP1GAAALDH1A1GPR35POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689645-A | Cyanoindole quinoline derivant as NIK inhibitor | 杨森制药有限公司 | 2019-04-26 | — | — | CN | disclosed |