Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 8/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17517932 | 0.86 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL20969747 | 0.84 | ADRB2 (0.46) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL13479564 | 0.83 | SLC6A4 (0.52) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL2492871 | 0.81 | MAPT (0.47) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL526383 | 0.80 | MAPT (0.58) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL29225756 | 0.79 | ADRB2 (0.42) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL29225758 | 0.79 | ADRB2 (0.42) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL1800842 | 0.79 | MAPT (0.45) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| SCHEMBL9320385 | 0.79 | MAPT (0.50) | ADRA2AADRA2BADRA2CMAPTLMNA | |
| Hydrochloric Acid SCHEMBL1923122 | 0.77 | MAPT (0.44) | ADRA2AADRA2BADRA2CMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349454-A | ENCAPSULATION OF A HYDROPHOBIC-SOLVENT SOLUTION OF A DIAMINODIARYL METHANE SULFONE DERIVATIVE | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1982-09-14 | — | — | US | disclosed |