Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11227950 | 1.00 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL11103790 | 0.74 | TSHR (0.48) | TSHRALDH1A1TDP1 | |
| Bromide SCHEMBL11100291 | 0.74 | TSHR (0.48) | TSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10930879 | 0.74 | PIK3CD (0.31) | — | |
| SCHEMBL246846 | 0.72 | — | — | |
| SCHEMBL304 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL3361978 | 0.72 | TSHR (0.46) | TSHRALDH1A1TDP1 | |
| Bromide SCHEMBL1304119 | 0.72 | TSHR (0.46) | TSHRALDH1A1TDP1 | |
| Water SCHEMBL16146551 | 0.72 | — | — | |
| SCHEMBL10805593 | 0.71 | TSHR (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357280-A | Use of tertiary phosphines in photographic silver dye bleach materials | CIBA-GEIGY AG (CH) | 1982-11-02 | — | — | US | disclosed |
| US-4138256-A | Method of processing photographic silver dye bleach materials | CIBA-GEIGY AG (CH) | 1979-02-06 | — | — | US | disclosed |