Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11100291 | 0.97 | TSHR (0.48) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL3361978 | 0.93 | TSHR (0.46) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL11103790 | 0.90 | TSHR (0.48) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Bromide SCHEMBL9658595 | 0.79 | TSHR (0.36) | TSHRALDH1A1TDP1SLC1A2 | |
| Bromide SCHEMBL11526442 | 0.75 | DNM1 (0.62) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL30395263 | 0.75 | TSHR (0.48) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL11236841 | 0.73 | TSHR (0.59) | TSHRALDH1A1TDP1 | |
| SCHEMBL10338939 | 0.72 | TSHR (0.50) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Iodide SCHEMBL11223368 | 0.72 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| Iodide SCHEMBL11227950 | 0.72 | TSHR (0.39) | TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4187214-A | Fire retardant adhesive polyolefin compositions | PHILLIPS PETROLEUM COMPANY (US) | 1980-02-05 | — | — | US | claimed |
| US-3940547-A | Adhesive polyolefin composition | PHILLIPS PETROLEUM COMPANY (US) | 1976-02-24 | — | — | US | claimed |
| CN-118185219-A | High-performance flame-retardant thermoplastic elastomer sealing material and preparation method and application thereof | 合诚技术股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-115916922-A | Thermally conductive phase change compositions, methods of manufacture thereof, and articles comprising the same | 罗杰斯公司 | 2023-04-04 | — | — | CN | disclosed |
| US-8722793-B2 | Polylactic acid resin composition, polylactic acid resin molded article and method for producing polylactic acid resin composition | FUJI XEROX CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-8258221-B2 | Polylactic acid-based resin composition and molded article of polylactic acid-based resin | FUJI XEROX CO., LTD. (JP) | 2012-09-04 | — | — | US | disclosed |
| US-8053516-B2 | Polylactic acid resin composition, method for producing polylactic acid resin composition, and polylactic acid resin molded article | FUJI XEROX CO., LTD. (JP) | 2011-11-08 | — | — | US | disclosed |
| US-20110207865-A1 | POLYLACTIC ACID-BASED RESIN COMPOSITION AND MOLDED ARTICLE OF POLYLACTIC ACID-BASED RESIN | FUJI XEROX CO., LTD. (JP) | 2011-08-25 | — | — | US | disclosed |
| US-20110207867-A1 | POLYLACTIC ACID RESIN COMPOSITION, METHOD FOR PRODUCING POLYLACTIC ACID RESIN COMPOSITION, AND POLYLACTIC ACID RESIN MOLDED ARTICLE | FUJI XEROX CO., LTD. (JP) | 2011-08-25 | — | — | US | disclosed |
| US-20110196089-A1 | POLYLACTIC ACID RESIN COMPOSITION, POLYLACTIC ACID RESIN MOLDED ARTICLE AND METHOD FOR PRODUCING POLYLACTIC ACID RESIN COMPOSITION | FUJI XEROX CO., LTD. (JP) | 2011-08-11 | — | — | US | disclosed |
| EP-1630195-B1 | Composite composition and molding using the same | SONY CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| EP-0280026-A2 | Copolyester fiber | TEIJIN LIMITED (JP) | 1988-08-31 | — | — | EP | disclosed |
| US-4621114-A | Propylene resin composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1986-11-04 | — | — | US | disclosed |
| EP-0042440-B1 | FIRE RETARDANT ORGANIC HIGH MOLECULAR COMPOSITION | ACOME, SOCIETE COOPERATIVE DE TRAVAILLEURS (FR) | 1985-03-27 | — | — | EP | disclosed |
| EP-0132968-A2 | Propylene resin composition | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1985-02-13 | — | — | EP | disclosed |
| US-4410648-A | CYCLIC ANHYDRIDE OR IMIDE, INORGANIC POWDER, POLYUNSATURATED MONOMER | DAINICHI-NIPPON CABLES, LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4395519-A | CRYSTALLINE POLYPROPYLENE AND ETHYLENE-PROPYLENE RANDOM COPOLYMER | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1983-07-26 | — | — | US | disclosed |
| EP-0042440-A1 | FIRE RETARDANT ORGANIC HIGH MOLECULAR COMPOSITION | ACOME, SOCIETE COOPERATIVE DE TRAVAILLEURS (FR) | 1981-12-30 | — | — | EP | disclosed |
| US-4187214-A | Fire retardant adhesive polyolefin compositions | PHILLIPS PETROLEUM COMPANY (US) | 1980-02-05 | — | — | US | disclosed |
| US-3940547-A | Adhesive polyolefin composition | PHILLIPS PETROLEUM COMPANY (US) | 1976-02-24 | — | — | US | disclosed |