Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.35 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11103790 | 0.97 | TSHR (0.48) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Bromide SCHEMBL1304119 | 0.93 | TSHR (0.46) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Bromide SCHEMBL11100291 | 0.90 | TSHR (0.48) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL11236841 | 0.79 | TSHR (0.59) | TSHRALDH1A1TDP1 | |
| SCHEMBL30395263 | 0.75 | TSHR (0.48) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL8466983 | 0.73 | ALDH1A1 (0.44) | TSHRALDH1A1TDP1 | |
| SCHEMBL10338939 | 0.72 | TSHR (0.50) | TSHRALDH1A1TDP1LOXLOXL3 | |
| Iodide SCHEMBL11227950 | 0.72 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| Iodide SCHEMBL11223368 | 0.72 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL11907969 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230407073-A1 | RESIN COMPOSITION, ADHESIVE, MULTILAYER BODY, SURFACE PROTECTION FILM, METHOD FOR PRODUCING SURFACE PROTECTION FILM, AND METHOD FOR PROTECTING SURFACE | MITSUI CHEMICALS, INC. (JP) | 2023-12-21 | — | — | US | disclosed |
| US-20220403072-A1 | RESIN COMPOSITION AND MOLDED ARTICLE | MITSUI CHEMICALS, INC. (JP) | 2022-12-22 | — | — | US | disclosed |
| US-8713882-B2 | Roofing product with zoned functional compositions and methods of making the same | CERTAINTEED CORPORATION (US) | 2014-05-06 | — | — | US | disclosed |
| US-20130022774-A1 | Roofing Product With Zoned Functional Compositions And Methods Of Making The Same | CERTAINTEED CORPORATION (US) | 2013-01-24 | — | — | US | disclosed |
| US-20100037548-A1 | Roofing Product With Zoned Functional Compositions And Methods Of Making The Same | CERTAINTEED CORPORATION (US) | 2010-02-18 | — | — | US | disclosed |
| US-6858676-B1 | Olefin derived copolymer | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2005-02-22 | — | — | US | disclosed |
| US-6773808-B2 | ADHESIVE LAYER COMPRISING AN OLEFIN COPOLYMER WITHA MOLECULAR WEIGHT DISTRIBUTION OF THE OLEFIN COPOLYMER, MW/ MN, OF NOT MORE THAN 3. | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2004-08-10 | — | — | US | disclosed |
| US-20040097650-A1 | Extrusion processability, heat resistance, flexibility, nonwhitening on bending; blend of hydrogenated vinyl aromatic-conjugated diene copolymer and thermoplastic resin | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-05-20 | — | — | US | disclosed |
| US-6562907-B2 | Having elastic recovery of from 70 to 100%; tubes, hoses | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |
| US-6525138-B2 | 5-95% by weight of a thermoplastic resin having a melt flow rate of 0.001-100 g/10 min. and a die swell ratio >/=1.7 and 95-5% of an olefin polymer; no crosslinking step needed | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-02-25 | — | — | US | disclosed |
| US-20020164491-A1 | Adhesive film | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-11-07 | — | — | US | disclosed |
| US-20020120065-A1 | Olefin polymer and thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-08-29 | — | — | US | disclosed |
| EP-1211287-A1 | Olefin polymer and thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-6391974-B1 | OLEFIN-BASED COPOLYMER | SUMITOMO CHEMICAL CO., LTD. (JP) | 2002-05-21 | — | — | US | disclosed |
| US-20020055592-A1 | Thermoplastic resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED | 2002-05-09 | — | — | US | disclosed |