Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652990 | 0.91 | TSHR (0.46) | ACE2TSHRFDPSCA1 | |
| SCHEMBL7434805 | 0.78 | FDPS (0.41) | ACE2TSHRFDPSCA1ALDH1A1 | |
| SCHEMBL28944520 | 0.76 | ACE2 (0.42) | ACE2TSHRFDPSALDH1A1DNM1 | |
| SCHEMBL18514502 | 0.74 | ACE2 (0.36) | ACE2TSHRFDPSCA1ALDH1A1 | |
| SCHEMBL8368919 | 0.74 | ACE2 (0.36) | ACE2TSHRFDPSCA1ALDH1A1 | |
| SCHEMBL1369967 | 0.74 | ALDH1A1 (0.46) | ACE2FDPSCA1ALDH1A1CA2 | |
| SCHEMBL14167783 | 0.74 | TSHR (0.39) | TSHRFDPSALDH1A1DNM1 | |
| SCHEMBL28639197 | 0.73 | FDPS (0.37) | ACE2TSHRFDPSCA1ALDH1A1 | |
| SCHEMBL14167668 | 0.72 | ACE2 (0.40) | ACE2FDPSCA1DNM1CA2 | |
| SCHEMBL4620404 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |