SCHEMBL11223581

SCHEMBL11223581

C=CC(=O)OC1CC2CC1C1C=CCC21

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
GAA P10253 2/20 0.35
CTNNB1 P35222 1/20 0.31
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22610196 1.00 POLB (0.41) POLBGAACTNNB1KDM4ELMNA
SCHEMBL91435 0.88 POLB (0.33) POLB
SCHEMBL31661865 0.88 POLB (0.33) POLB
SCHEMBL31261806 0.83 ATM (0.30)
SCHEMBL10339584 0.83 ATM (0.44) POLBGAARAB9ANPSR1
SCHEMBL9885421 0.81 TSHR (0.37) POLBGAA
SCHEMBL23542584 0.81 POLB (0.35) POLBGAA
SCHEMBL13714112 0.80 POLB (0.41) POLBGAALMNAMAPTMAPK1
SCHEMBL112485 0.80 POLB (0.41) POLBGAALMNAMAPTMAPK1
SCHEMBL23542587 0.79 TSHR (0.42) POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3962411-A1 HIGH REACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. (US) 2022-03-09 EP claimed
WO-2020225686-A1 HIGH REACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. (US) 2020-11-12 WO claimed
JP-57207637-A None JP disclosed
US-20260028439-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER JOHNSON & JOHNSON SURGICAL VISION INC (US) 2026-01-29 US disclosed
US-12460032-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2025-11-04 US disclosed
US-20240336868-A1 COMPOSITIONS COMPRISING ADAMANTYL ESTER-CONTAINING COMPOUNDS THE PROCTER & GAMBLE COMPANY 2024-10-10 US disclosed
US-20240218102-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. 2024-07-04 US disclosed
US-11958923-B2 Compositions with high refractive index and abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2024-04-16 US disclosed
US-20240018298-A1 OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS ExxonMobil Product Solutions Company 2024-01-18 US disclosed
US-20240018298-A1 OLEFINIC COMPOSITIONS COMPRISING HYDROCARBON RESINS ExxonMobil Product Solutions Company 2024-01-18 US disclosed
US-20230365822-A1 ELECTRON BEAM CURABLE INK AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2023-11-16 US disclosed
US-20200148908-A1 CROSSLINKED COATING COMPOSITIONS FOR PACKAGING ARTICLES SUCH AS FOOD AND BEVERAGE CONTAINERS SWIMC LLC 2020-05-14 US disclosed
WO-2020072776-A1 POLYMERS FOR SPECIALTY APPLICATIONS MATERIA, INC. (US) 2020-04-09 WO disclosed
US-7629423-B2 Alkene-acrylate-norbornene terpolymer and method for preparing the same LG CHEM, LTD. (KR) 2009-12-08 US disclosed
US-7629423-B2 Alkene-acrylate-norbornene terpolymer and method for preparing the same LG CHEM, LTD. (KR) 2009-12-08 US disclosed
US-20090191634-A1 (METH)ACRYLATE SURFACES FOR CELL CULTURE, METHODS OF MAKING AND USING THE SURFACES GERON CORPORATION 2009-07-30 US disclosed
US-20090191634-A1 (METH)ACRYLATE SURFACES FOR CELL CULTURE, METHODS OF MAKING AND USING THE SURFACES GERON CORPORATION 2009-07-30 US disclosed
US-20070255027-A1 ALKENE-ACRYLATE-NORBORNENE TERPOLYMER AND METHOD FOR PREPARING THE SAME LG CHEM, LTD. (KR) 2007-11-01 US disclosed
US-20070255027-A1 ALKENE-ACRYLATE-NORBORNENE TERPOLYMER AND METHOD FOR PREPARING THE SAME LG CHEM, LTD. (KR) 2007-11-01 US disclosed
JP-S57207637-A RESIN COMPOSITION SEKISUI CHEM CO LTD 1982-12-20 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028439-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER SMCHD1, MACF1, LAGE3 POLB 3786/4885GAA 4856/4885CTNNB1 2914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.