Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075059 | 0.84 | HTR2C (0.47) | IDO1LMNAALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL435089 | 0.81 | LMNA (0.49) | LMNAALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL30609047 | 0.80 | TRPM8 (0.40) | IDO1LMNAALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL9749197 | 0.80 | SSTR5 (0.37) | IDO1LMNAHPGDHTR2CSSTR5 | |
| SCHEMBL17208928 | 0.80 | HTR2C (0.36) | HTR2CDRD2HTR2ATRPM8L3MBTL1 | |
| SCHEMBL8376689 | 0.78 | AKT1 (0.41) | LMNAL3MBTL1 | |
| SCHEMBL20819453 | 0.78 | AKT1 (0.41) | LMNAL3MBTL1 | |
| SCHEMBL9333780 | 0.78 | HPGD (0.40) | IDO1LMNAALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL9928158 | 0.77 | HPGD (0.51) | LMNARAB9AKMT2AMALT1HPGD | |
| SCHEMBL13422911 | 0.77 | IDO1 (0.36) | IDO1LMNAALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156575-A1 | NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2009-06-18 | — | — | US | disclosed |
| EP-1330460-B1 | BENZOXAZINONE DERIVATIVES, THEIR PREPARATION AND USE | SMITHKLINE BEECHAM PLC (GB) | 2007-03-21 | — | — | EP | disclosed |
| US-4316912-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-02-23 | — | — | US | disclosed |
| EP-0000936-A1 | 4-Indanyl esters of N-alkyl carbamic acid, processes for their preparation and their use as pesticides | BAYER AG (DE) | 1979-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156575-A1 | NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES | CCR8, CCR1, CCR10 | IDO1 1564/4885LMNA 2943/4885ALDH1A1 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.