Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 4/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MEN1 | O00255 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27401551 | 0.75 | AKR1B1 (0.44) | AKR1B1XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL14001007 | 0.74 | TLR8 (0.48) | AKR1B1XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL9046562 | 0.74 | AKR1B1 (0.46) | AKR1B1XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL27705376 | 0.71 | AKR1B1 (0.46) | AKR1B1XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL18548999 | 0.71 | AKR1B1 (0.44) | AKR1B1XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL11336662 | 0.69 | AKR1B1 (0.48) | AKR1B1XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL22457218 | 0.69 | XIAP (0.48) | AKR1B1XIAPKMT2AMEN1ALDH1A1 | |
| SCHEMBL10884842 | 0.67 | TDP1 (0.46) | AKR1B1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1801464 | 0.67 | ALDH1A1 (0.52) | XIAPKMT2AMEN1ALDH1A1HPGD | |
| Bromide SCHEMBL4961408 | 0.65 | ALDH1A1 (0.50) | XIAPKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343888-A | Use of radiation crosslinkable polyesters and polyesterethers in printing plates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-08-10 | — | — | US | disclosed |
| US-4284710-A | FROM DIEPOXIDE AND AROMATIC UNSATURATED DICARBOXYLIC ACID OR HYDROXY ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-08-18 | — | — | US | disclosed |