Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046562 | 0.83 | AKR1B1 (0.46) | AKR1B1XIAPMEN1KMT2APOLB | |
| SCHEMBL8956490 | 0.83 | AKR1B1 (0.46) | TLR8TLR7AKR1B1XIAPMEN1 | |
| SCHEMBL27401551 | 0.80 | AKR1B1 (0.44) | TLR8TLR7AKR1B1XIAPMEN1 | |
| SCHEMBL27705376 | 0.79 | AKR1B1 (0.46) | AKR1B1XIAPMEN1KMT2APOLB | |
| SCHEMBL18548999 | 0.79 | AKR1B1 (0.44) | AKR1B1XIAPMEN1KMT2APOLB | |
| SCHEMBL11336662 | 0.77 | AKR1B1 (0.48) | AKR1B1XIAPMEN1KMT2APOLB | |
| SCHEMBL2170681 | 0.77 | RAB9A (0.53) | TLR8TLR7XIAPMEN1KMT2A | |
| SCHEMBL29843187 | 0.77 | RAB9A (0.53) | TLR8TLR7XIAPMEN1KMT2A | |
| SCHEMBL4139521 | 0.75 | RAB9A (0.51) | TLR8TLR7XIAPMEN1KMT2A | |
| SCHEMBL11223737 | 0.74 | AKR1B1 (0.43) | AKR1B1XIAPMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7470712-B2 | Amino-benzazoles as P2Y1 receptor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-30 | — | — | US | disclosed |