Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10359295 | 0.83 | NOS2 (0.46) | NOS2TP53HTR2ADRD2HTR7 | |
| SCHEMBL7172382 | 0.83 | CSNK2A1 (0.59) | CSNK2A1TP53RORCHTTLMNA | |
| SCHEMBL21340747 | 0.81 | HTR2A (0.47) | HTR2AALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL14039634 | 0.81 | CSNK2A1 (0.49) | CSNK2A1RORCHTR2ALMNAPOLB | |
| SCHEMBL16606237 | 0.81 | CSNK2A1 (0.44) | CSNK2A1RORCHTR2ALMNAPOLB | |
| SCHEMBL25974456 | 0.81 | HTR2A (0.46) | CSNK2A1RORCHTR2AHTTLMNA | |
| SCHEMBL19121462 | 0.79 | CSNK2A1 (0.43) | NOS2CSNK2A1RORCHTTLMNA | |
| SCHEMBL17744335 | 0.79 | HSD17B10 (0.45) | CSNK2A1RORCHTR2AHTTLMNA | |
| SCHEMBL2372500 | 0.79 | CSNK2A1 (0.47) | NOS2CSNK2A1RORCHTR2AHTT | |
| SCHEMBL19088280 | 0.79 | TRPV4 (0.46) | CSNK2A1TP53HTR2AHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346244-A | Preparation of chloroalkoxybenzenes | RHONE-POULENC INDUSTRIES (FR) | 1982-08-24 | — | — | US | claimed |
| US-20190002448-A1 | SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF | Karyopharm Therapeutics Inc. | 2019-01-03 | — | — | US | disclosed |
| WO-2017117406-A1 | SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF | Karyopharm Therapeutics Inc. (US) | 2017-07-06 | — | — | WO | disclosed |
| US-4346244-A | Preparation of chloroalkoxybenzenes | RHONE-POULENC INDUSTRIES (FR) | 1982-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190002448-A1 | SUBSTITUTED BENZOFURANYL AND BENZOXAZOLYL COMPOUNDS AND USES THEREOF | BCL6, MALT1, BCL3 | NOS2 4701/4885CSNK2A1 856/4885TP53 684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.