SCHEMBL11224059

SCHEMBL11224059

CCCCCCCCCCCCCCCC(OOCCCC)OC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.42
GPR84 Q9NQS5 7/20 0.42
FFAR1 O14842 2/20 0.42
MAPT P10636 1/20 0.41
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
FFAR4 Q5NUL3 1/20 0.39
ACE2 Q9BYF1 1/20 0.39
ZDHHC7 Q9NXF8 1/20 0.38
FAAH O00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28353990 0.90 ALDH1A1 (0.35) GPR84FFAR1MAPTLCKPPARD
SCHEMBL11224048 0.88 SMPD1 (0.43) SMPD1GPR84FFAR1MAPTLCK
SCHEMBL11231305 0.88 SMPD1 (0.43) SMPD1GPR84FFAR1MAPTLCK
SCHEMBL28326424 0.84 GPR84 (0.52) SMPD1GPR84FFAR1MAPTLCK
SCHEMBL27584516 0.82 SMPD1 (0.48) SMPD1GPR84FFAR1MAPTLCK
SCHEMBL17823981 0.80 SMPD1 (0.41) SMPD1GPR84ZDHHC7
SCHEMBL8460650 0.79 SMPD1 (0.45) SMPD1GPR84FFAR1MAPTLCK
SCHEMBL9842737 0.79 SMPD1 (0.45) SMPD1GPR84FFAR1MAPTLCK
SCHEMBL9751259 0.78 SMPD1 (0.44) SMPD1GPR84MAPT
SCHEMBL2770051 0.78 ACE2 (0.37) GPR84FFAR1MAPTLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0009268-B1 PROCESS FOR CROSS-LINKING SHAPED NON-POLAR SYNTHETIC RESINS AND ELECTRIC OBJECTS INSULATED WITH SAID CROSSLINKED RESINS AKZO N.V. (NL) 1982-12-01 EP disclosed
US-4322273-A TREATING A MIXTURE OF ACYCLIC OLEFIN-BASED POLYMER AND POLAR PERESTER, PERKETAL, OR ESTER- CONTAINING PEROXY COMPOUND; WITH HIGH-FREQUENY ALTERNATING CURRENT DIELECTRICS AKZONA INCORPORATED (US) 1982-03-30 US disclosed
EP-0009268-A1 Process for cross-linking shaped non-polar synthetic resins and electric objects insulated with said crosslinked resins AKZO N.V. (NL) 1980-04-02 EP disclosed