Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188228 | 0.89 | IDO1 (0.36) | IDO1AGXTCHRNB2CHRNA4PPARG | |
| SCHEMBL11233881 | 0.81 | IDO1 (0.50) | IDO1AGXTCHRNB2CHRNA4PPARG | |
| SCHEMBL11230641 | 0.79 | AGXT (0.48) | IDO1AGXTMAOBCA1CA2 | |
| SCHEMBL11265351 | 0.79 | RXRA (0.40) | PPARGPPARAL3MBTL1KMT2A | |
| SCHEMBL872358 | 0.78 | TSHR (0.48) | IDO1AGXTMAOBCA1CA2 | |
| SCHEMBL11232686 | 0.76 | IDO1 (0.52) | IDO1AGXTMAOBAPPCA1 | |
| SCHEMBL9466763 | 0.75 | IDO1 (0.30) | IDO1 | |
| SCHEMBL6802731 | 0.75 | IDO1 (0.44) | IDO1MAOBAPPCA1CA2 | |
| SCHEMBL10819594 | 0.74 | IDO1 (0.52) | IDO1AGXTCHRNB2CHRNA4PPARG | |
| SCHEMBL12290347 | 0.73 | SLC6A2 (0.44) | IDO1AGXTPPARGPPARASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |