Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9188228 | 0.88 | IDO1 (0.36) | TSHRSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL11448991 | 0.88 | TSHR (0.41) | TSHRSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL871423 | 0.88 | TSHR (0.41) | TSHRSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL14754591 | 0.86 | ALDH1A1 (0.40) | TSHRSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL27876875 | 0.85 | PSMB5 (0.41) | TSHRSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL9187375 | 0.84 | IDO1 (0.39) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL2319770 | 0.84 | ALDH1A1 (0.47) | SLC1A3SLC1A2SLC1A1KMT2ACYP1A2 | |
| SCHEMBL18555483 | 0.83 | TSHR (0.44) | TSHRSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL7011964 | 0.82 | TSHR (0.48) | TSHRSLC1A3SLC1A2SLC1A1KMT2A | |
| SCHEMBL11265351 | 0.78 | RXRA (0.40) | TSHRKMT2AALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570625-B2 | 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | NOVARTIS AG (CH) | 2026-03-10 | — | — | US | disclosed |
| US-12421251-B2 | Cystic fibrosis transmembrane conductance regulator modulating agents | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-09-23 | — | — | US | disclosed |
| WO-2025076632-A1 | COMPOUNDS AND USES THEREOF | FIBROCOR THERAPEUTICS INC. (CA) | 2025-04-17 | — | — | WO | disclosed |
| CN-112261970-B | 3- (5-Hydroxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and their use in the treatment of IKAROS family zinc finger 2 (IKZF 2) dependent diseases | 诺华股份有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-119241499-A | 3- (5-Hydroxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| EP-2895488-B1 | TRICYCLIC GYRASE INHIBITORS FOR USE AS ANTIBACTERIAL AGENTS | MERCK SHARP & DOHME LLC (US) | 2024-12-11 | — | — | EP | disclosed |
| CN-113905785-B | Cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2024-07-19 | — | — | CN | disclosed |
| EP-4335498-A1 | CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MODULATING AGENTS | Vertex Pharmaceuticals Incorporated (US) | 2024-03-13 | — | — | EP | disclosed |
| EP-4306111-A2 | 3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF | Novartis AG (CH) | 2024-01-17 | — | — | EP | disclosed |
| EP-3946595-B1 | CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MODULATING AGENTS | VERTEX PHARMA (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2004099224-A1 | CARBOPLATIN-TYPE PLATINUM (II) COMPLEXES | UNIVERSITÄT REGENSBURG (DE) | 2004-11-18 | — | — | WO | disclosed |
| US-6080750-A | FOR PROPHYLAXIS AND TREATMENT OF DISEASES CAUSED BY INFECTION BY ROTAVIRUS | NIPPON SHOJI KAISHA LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0806418-A2 | Novel pyrimidine compound and anti-rotavirus agent | NIPPON SHOJI KAISHA, LIMITED (JP) | 1997-11-12 | — | — | EP | disclosed |
| EP-0454270-B1 | Catalyst compositions | SHELL INT RESEARCH (NL) | 1993-12-15 | — | — | EP | disclosed |
| US-5229343-A | Polymerization process | SHELL OIL COMPANY (US) | 1993-07-20 | — | — | US | disclosed |
| US-5171832-A | POLYMERIZATION OF CARBON MONOXIDE/OLEFIN WITH P BIDENTATE LIGAND HAVING (1) ALKOXY PHENYL P GROUP AND (2) MONOSUBSTITUTED DIVALENT BRIDGING GROUP | SHELL OIL COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0454270-A1 | Catalyst compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-10-30 | — | — | EP | disclosed |
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| EP-0045964-A1 | Derivatives of 3-amino-1,2-propane diol | CIBA-GEIGY AG (CH) | 1982-02-17 | — | — | EP | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12570625-B2 | 3-(5-hydroxy-1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof | IKZF1, IKZF2, BCL6 | TSHR 3099/4885SLC1A3 2678/4885SLC1A2 2552/4885 |
| US-12421251-B2 | Cystic fibrosis transmembrane conductance regulator modulating agents | CFTR, SCNN1G, CLCN2 | TSHR 947/4885SLC1A3 795/4885SLC1A2 857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.