SCHEMBL11224285

SCHEMBL11224285

Nc1cc(S(=O)(=O)O)c2cc(S(=O)(=O)O)cc(S(=O)(=O)O)c2c1.Nc1ccc(N=Nc2ccc(S(=O)(=O)O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 5/20 0.53
SUMO2 P61956 4/20 0.53
SUMO1 P63165 4/20 0.53
SENP7 Q9BQF6 4/20 0.53
ALDH1A1 P00352 3/20 0.50
NT5E P21589 2/20 0.50
TSHR P16473 1/20 0.50
CA12 O43570 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
POLB P06746 1/20 0.47
CYP2D6 P10635 1/20 0.47
MEN1 O00255 1/20 0.44
APP P05067 1/20 0.44
MAPT P10636 1/20 0.44
THRB P10828 1/20 0.44
HPGD P15428 1/20 0.44
ALOX12 P18054 1/20 0.44
SNCA P37840 1/20 0.44
RECQL P46063 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7869667 0.89 SENP2 (0.52) SENP2SUMO2SUMO1SENP7ALDH1A1
SCHEMBL7107286 0.89 SENP2 (0.52) SENP2SUMO2SUMO1SENP7ALDH1A1
SCHEMBL152904 0.83 NT5E (0.50) SENP2SUMO2SUMO1SENP7ALDH1A1
SCHEMBL29961913 0.83 NT5E (0.50) SENP2SUMO2SUMO1SENP7ALDH1A1
SCHEMBL30726813 0.83 NT5E (0.50) SENP2SUMO2SUMO1SENP7ALDH1A1
SCHEMBL5752505 0.82 TSHR (0.75) SENP2SUMO2SUMO1SENP7ALDH1A1
SCHEMBL1485997 0.82 TSHR (0.75) SENP2SUMO2SUMO1SENP7ALDH1A1
SCHEMBL11682855 0.80 SENP2 (0.59) SENP2SUMO2SUMO1SENP7ALDH1A1
SCHEMBL11682850 0.80 SENP2 (0.59) SENP2SUMO2SUMO1SENP7ALDH1A1
SCHEMBL11590196 0.80 TSHR (0.72) SENP2SUMO2SUMO1SENP7ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0024668-B1 REACTIVE DYESTUFFS AND THEIR USE IN DYEING AND PRINTING HYDROXYL GROUPS AND NITROGEN CONTAINING MATERIALS BAYER AG (DE) 1983-04-13 EP disclosed
EP-0024668-A2 Reactive dyestuffs and their use in dyeing and printing hydroxyl groups and nitrogen containing materials BAYER AG (DE) 1981-03-11 EP disclosed