SCHEMBL7869667

SCHEMBL7869667

Nc1ccc(N=Nc2cc(S(=O)(=O)O)c3cc(S(=O)(=O)O)cc(S(=O)(=O)O)c3c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP2 Q9HC62 6/20 0.52
SUMO2 P61956 5/20 0.52
SUMO1 P63165 5/20 0.52
SENP7 Q9BQF6 5/20 0.52
ATIC P31939 1/20 0.52
SENP1 Q9P0U3 4/20 0.47
SENP3 Q9H4L4 3/20 0.47
CA12 O43570 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
ALDH1A1 P00352 3/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
APP P05067 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
ALOX12 P18054 1/20 0.46
SNCA P37840 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7107286 1.00 SENP2 (0.52) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL11224285 0.89 SENP2 (0.53) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL13763487 0.85 CYP1A2 (0.52) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL4898001 0.84 SENP2 (0.71) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL3915968 0.84 SENP2 (0.71) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL10393442 0.83 SENP2 (0.77) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL11682850 0.82 SENP2 (0.59) SENP2SUMO2SUMO1SENP7SENP1
SCHEMBL11682855 0.82 SENP2 (0.59) SENP2SUMO2SUMO1SENP7SENP1
SCHEMBL13112900 0.80 SENP2 (0.49) SENP2SUMO2SUMO1SENP7ATIC
SCHEMBL9132078 0.80 ENPP2 (0.54) SENP2SUMO2SUMO1SENP7ATIC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6307034-B1 REACTIVE DYES CIBA SPECIALTY CHEMICALS CORPORATION 2001-10-23 US disclosed