SCHEMBL11224409

SCHEMBL11224409

N#CCCP(=O)(O)CCC#N

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TYMS P04818 1/20 0.32
LOX P28300 1/20 0.32
LOXL3 P58215 1/20 0.32
LOXL2 Q9Y4K0 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GABBR2 O75899 1/20 0.31
GABRR1 P24046 1/20 0.31
GABBR1 Q9UBS5 1/20 0.31
NLRP3 Q96P20 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9417045 0.88 GABBR2 (0.39) ALDH1A1TDP1TSHRMEN1KMT2A
SCHEMBL2352079 0.85
SCHEMBL11309485 0.82 ALDH1A1 (0.39) ALDH1A1TDP1LOXLOXL3LOXL2
SCHEMBL6511678 0.82
SCHEMBL8386899 0.78
SCHEMBL24624048 0.75 ALDH1A1 (0.44) ALDH1A1TDP1LOXLOXL3LOXL2
SCHEMBL517724 0.75 ALDH1A1 (0.44) ALDH1A1TDP1LOXLOXL3LOXL2
Butane SCHEMBL7714667 0.74 LPAR3 (0.44) ALDH1A1TYMSTSHR
SCHEMBL19313070 0.74 TSHR (0.40) ALDH1A1TDP1TSHRNLRP3
SCHEMBL24624068 0.73 ALDH1A1 (0.41) ALDH1A1TDP1LOXLOXL3LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4321187-A HOMOGENOUS BLEND WITH RUBBER-MODIFIED POLYSTYRENE; DIISOBUTYL-OR DICYCLOHEXYLPHOSPHINIC ACID AMERICAN CYANAMID COMPANY (US) 1982-03-23 US disclosed