Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 3/20 | 0.61 |
| ▸ | CDK2 | P24941 | 3/20 | 0.61 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.61 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23213713 | 0.88 | CCNE1 (0.66) | CCNE1CDK2CDK5FDPSALDH1A1 | |
| SCHEMBL233711 | 0.83 | CDK2 (0.60) | CCNE1CDK2CDK5FDPSLMNA | |
| SCHEMBL11225514 | 0.81 | ALDH1A1 (0.58) | CCNE1CDK2CDK5FDPSALDH1A1 | |
| SCHEMBL19364715 | 0.79 | MEN1 (0.63) | CCNE1CDK2CDK5FDPSTSHR | |
| SCHEMBL11919154 | 0.78 | ALDH1A1 (0.70) | CCNE1CDK2CDK5FDPSALDH1A1 | |
| SCHEMBL5653949 | 0.78 | CCNE1 (0.55) | CCNE1CDK2CDK5FDPSALDH1A1 | |
| SCHEMBL14476225 | 0.78 | SMN1; SMN2 (0.57) | CCNE1CDK2CDK5FDPSALDH1A1 | |
| SCHEMBL3040422 | 0.77 | RAB9A (0.57) | ALDH1A1LMNANPC1TP53RAB9A | |
| SCHEMBL8834765 | 0.75 | CCNE1 (0.52) | CCNE1CDK2CDK5FDPSALDH1A1 | |
| SCHEMBL23240244 | 0.75 | CCNE1 (0.64) | CCNE1CDK2CDK5ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321372-A | Antiulcer thiazol-2-ylcarbamoyl-carboxylic acids, esters and amides | PFIZER INC. (US) | 1982-03-23 | — | — | US | disclosed |