Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | CD81 | P60033 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224557 | 1.00 | TSHR (0.39) | TSHRALDH1A1PPARGBACE1CD81 | |
| SCHEMBL480078 | 0.83 | BACE1 (0.41) | PPARGBACE1CD81KDM4EATM | |
| SCHEMBL6864095 | 0.82 | TSHR (0.38) | TSHRALDH1A1KDM4EATMPOLB | |
| SCHEMBL28682934 | 0.79 | PPARG (0.35) | TSHRALDH1A1PPARGBACE1CD81 | |
| SCHEMBL11737217 | 0.78 | PPARG (0.40) | TSHRPPARGBACE1CD81KDM4E | |
| SCHEMBL11737202 | 0.78 | PPARG (0.40) | TSHRPPARGBACE1CD81KDM4E | |
| SCHEMBL435540 | 0.78 | LMNA (0.42) | ALDH1A1PPARGBACE1CD81KDM4E | |
| SCHEMBL2918368 | 0.78 | KDM4E (0.45) | ALDH1A1PPARGBACE1CD81KDM4E | |
| SCHEMBL2918372 | 0.78 | KDM4E (0.45) | ALDH1A1PPARGBACE1CD81KDM4E | |
| SCHEMBL33626 | 0.78 | LMNA (0.42) | ALDH1A1PPARGBACE1CD81KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4229431-A | IN SITU POLYMERIZATION | LEE PHARMACEUTICALS (US) | 1980-10-21 | — | — | US | claimed |
| US-4104333-A | COMPOSITIONS CONTAINING CROSSLINKING MONOMERS, MONOACRYLATES, INITIATORS AND ACCELERATORS | LEE PHARMACEUTICALS (US) | 1978-08-01 | — | — | US | claimed |
| CN-1291250-C | Phase dfiference film comprising polymer film having ultraviolet curable resin composition for alignment film and liquid crystalline compound | NIPPON KAYAKU KK (JP) | 2006-12-20 | — | — | CN | disclosed |
| CN-1493007-A | Phase dfiference film comprising polymer film having ultraviolet curable resin composition for alignment film and liquid crystalline compound | 日本化药株式会社 | 2004-04-28 | — | — | CN | disclosed |
| US-4340532-A | CURABLE ORTHODONTIC COMPOSITION | LEE PHARMACEUTICALS, INC. (US) | 1982-07-20 | — | — | US | disclosed |
| US-4340529-A | CURABLE ACRYLATE PRIMER | LEE PHARMACEUTICALS, INC. (US) | 1982-07-20 | — | — | US | disclosed |
| US-4260701-A | Formulation for self-curing artificial fingernails containing methoxyethyl methacrylate | LEE PHARMACEUTICALS (US) | 1981-04-07 | — | — | US | disclosed |
| US-4229431-A | IN SITU POLYMERIZATION | LEE PHARMACEUTICALS (US) | 1980-10-21 | — | — | US | disclosed |
| US-4104333-A | COMPOSITIONS CONTAINING CROSSLINKING MONOMERS, MONOACRYLATES, INITIATORS AND ACCELERATORS | LEE PHARMACEUTICALS (US) | 1978-08-01 | — | — | US | disclosed |