Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11224593 | 0.82 | TSHR (0.39) | TSHRALDH1A1POLBKDM4EATM | |
| SCHEMBL11224557 | 0.82 | TSHR (0.39) | TSHRALDH1A1POLBKDM4EATM | |
| SCHEMBL528543 | 0.78 | LMNA (0.39) | POLBTDP1KDM4EATM | |
| SCHEMBL528542 | 0.78 | LMNA (0.39) | POLBTDP1KDM4EATM | |
| SCHEMBL1556596 | 0.77 | POLB (0.41) | ALDH1A1POLBKDM4EATM | |
| SCHEMBL11576254 | 0.75 | ALDH1A1 (0.41) | TSHRALDH1A1POLBKDM4EATM | |
| SCHEMBL11576257 | 0.75 | ALDH1A1 (0.41) | TSHRALDH1A1POLBKDM4EATM | |
| Acrylic Acid SCHEMBL28857979 | 0.74 | LMNA (0.39) | TSHRALDH1A1FGFR4TDP1 | |
| SCHEMBL11511188 | 0.73 | EP300 (0.37) | ALDH1A1POLBTDP1KDM4E | |
| SCHEMBL11507795 | 0.73 | POLB (0.35) | ALDH1A1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818718-B2 | IMPROVED SEPARATION OF PROTEINS, ENZYMES, PEPTIDES, OLIGONUCLEOTIDES, POLYNUCLEOTIDES, AND CARBOHYDRATES | THE UNIVERSITY OF MELBOURNE (AU) | 2004-11-16 | — | — | US | disclosed |
| US-20010020079-A1 | Electrophoresis gels and cross-linking agents for their preparation | THE UNIVERSITY OF MELBOURNE | 2001-09-06 | — | — | US | disclosed |
| US-6197906-B1 | ASSYMETRIC AGENTS SUCH AS (2-METHACRYLOYLOXYETHYL)ACRYLAMIDE, (2-ACRYLOYLOXYETHYL)METHACRYLAMIDE, AND (N-METHYL-N-ACRYLOYLAMINO)ETHYL METHACRYLATE | THE UNIVERSITY OF MELBOURNE (AU) | 2001-03-06 | — | — | US | disclosed |
| EP-0920412-A4 | ELECTROPHORESIS GELS AND CROSS-LINKING AGENTS FOR THEIR PREPARATION | UNIV MELBOURNE (AU) | 2000-08-02 | — | — | EP | disclosed |
| EP-0920412-A1 | ELECTROPHORESIS GELS AND CROSS-LINKING AGENTS FOR THEIR PREPARATION | THE UNIVERSITY OF MELBOURNE (AU) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998001419-A1 | ELECTROPHORESIS GELS AND CROSS-LINKING AGENTS FOR THEIR PREPARATION | THE UNIVERSITY OF MELBOURNE (AU) | 1998-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010020079-A1 | Electrophoresis gels and cross-linking agents for their preparation | MACF1, ZYX, F12 | TSHR 4643/4885ALDH1A1 794/4885POLB 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.