Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899959 | 0.85 | HTT (0.61) | HTTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL10677656 | 0.82 | HTT (0.61) | HTTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL11083457 | 0.80 | HTT (0.51) | HTTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL10954923 | 0.79 | HTT (0.61) | HTTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL11182243 | 0.79 | BACE1 (0.53) | HTTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL11008454 | 0.77 | HTT (0.51) | HTTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL10974652 | 0.77 | HTT (0.51) | HTTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL7898481 | 0.77 | HTT (0.51) | HTTMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL3722747 | 0.76 | HTT (0.47) | HTTMEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL9420221 | 0.76 | ALDH1A1 (0.54) | HTTMEN1KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57072968-A | — | — | None | — | — | JP | disclosed |
| JP-S5772968-A | ANILINE DERIVATIVE AND ITS PREPARATION | NISSAN CHEM IND LTD | 1982-05-07 | — | — | JP | disclosed |