Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3720887 | 0.84 | HTT (0.47) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3724731 | 0.82 | ALDH1A1 (0.47) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL10973495 | 0.81 | ALDH1A1 (0.51) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3719822 | 0.80 | ALDH1A1 (0.51) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3718562 | 0.79 | HTT (0.62) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3719825 | 0.79 | ALDH1A1 (0.45) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL10677656 | 0.76 | HTT (0.61) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11224604 | 0.76 | HTT (0.61) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL30891066 | 0.75 | TLR9 (0.50) | HTTRAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL3566631 | 0.75 | TLR9 (0.50) | HTTRAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |