Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2343853 | 0.88 | FBP1 (0.58) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL15234446 | 0.83 | FBP1 (0.54) | FBP1PRMT1AKR1C3MEN1KMT2A | |
| SCHEMBL11236417 | 0.81 | FBP1 (0.52) | FBP1ALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8507853 | 0.81 | FBP1 (0.59) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL1749791 | 0.74 | FBP1 (1.00) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL7200178 | 0.74 | AKR1C3 (0.55) | FBP1AKR1C3ALDH1A1TSHRGLA | |
| SCHEMBL2918522 | 0.74 | AKR1C3 (0.55) | FBP1AKR1C3ALDH1A1TSHRGLA | |
| SCHEMBL30937972 | 0.74 | AKR1C3 (0.55) | FBP1AKR1C3ALDH1A1TSHRGLA | |
| SCHEMBL1032131 | 0.74 | FBP1 (1.00) | FBP1PRMT1AKR1C3ALDH1A1TSHR | |
| SCHEMBL3248323 | 0.74 | AKR1C3 (0.55) | FBP1AKR1C3ALDH1A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318986-A | Enzyme assays | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-03-09 | — | — | US | disclosed |
| EP-0007372-A1 | Methods and reagents for the assay of enzymes | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1980-02-06 | — | — | EP | disclosed |
| WO-1979000255-A1 | ENZYME ASSAYS | NAT RES DEV (GB) | 1979-05-17 | — | — | WO | disclosed |