Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2343853 | 0.85 | FBP1 (0.58) | FBP1PRMT1MEN1KMT2AALDH1A1 | |
| SCHEMBL11224683 | 0.81 | FBP1 (0.59) | FBP1PRMT1MAPTNPSR1MEN1 | |
| SCHEMBL12122140 | 0.77 | SMN1; SMN2 (0.63) | FBP1PRMT1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL15234446 | 0.77 | FBP1 (0.54) | FBP1PRMT1MAPTMEN1KMT2A | |
| SCHEMBL27704199 | 0.77 | SMN1; SMN2 (0.63) | FBP1PRMT1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL27947569 | 0.76 | LMNA (0.51) | FBP1PRMT1MEN1KMT2ATDP1 | |
| SCHEMBL1749791 | 0.75 | FBP1 (1.00) | FBP1PRMT1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL1127238 | 0.75 | FBP1 (1.00) | FBP1PRMT1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL1032131 | 0.75 | FBP1 (1.00) | FBP1PRMT1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL9328703 | 0.74 | FBP1 (0.64) | FBP1PRMT1ALDH1A1TSHRAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923581-A1 | 4-SUBSTITUTED BETA-CARBOLINES AS IMMUNOMODULATORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006719-A1 | 4-SUBSTITUTED BETA-CARBOLINES AS IMMUNOMODULATORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1998-02-19 | — | — | WO | disclosed |