SCHEMBL11224697

SCHEMBL11224697

C=CCN(c1ccccc1)c1ccc[nH]1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
S1PR1 P21453 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 1/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
HTR1D P28221 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39946 0.78 ESR1 (0.44) ESR1ALDH1A1LMNAHTTS1PR1
SCHEMBL9818045 0.78 ESR1 (0.44) ESR1ALDH1A1LMNAHTTS1PR1
Water SCHEMBL10786878 0.76 ESR1 (0.43) ESR1ALDH1A1LMNAHTTS1PR1
Ammonia Solution, Strong SCHEMBL28398668 0.76 ESR1 (0.43) ESR1ALDH1A1LMNAHTTS1PR1
SCHEMBL761137 0.72 MEN1 (0.38) ALDH1A1LMNAKDM4EMEN1KMT2A
SCHEMBL4047348 0.72 ESR1 (0.38) ESR1ALDH1A1LMNAHTTS1PR1
SCHEMBL11342828 0.71 TAAR1 (0.43) ESR1ALDH1A1LMNAHTTS1PR1
SCHEMBL3265246 0.71 ALDH1A1 (0.41) ESR1ALDH1A1LMNAS1PR1TAAR1
SCHEMBL11342835 0.70 ESR1 (0.35) ESR1ALDH1A1LMNAHTTS1PR1
SCHEMBL5599380 0.70 ALDH1A1 (0.39) ALDH1A1TAAR1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0010166-B1 N-(1,2-AZOLYL)ALKYL-CHLOROACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1982-10-27 EP claimed
US-4392882-A N-N-Bis(haloacyl)-diaza-cycloalkanes for protecting plants from herbicide damage BAYER AKTIENGESELLSCHAFT (DE) 1983-07-12 US disclosed
EP-0010166-B1 N-(1,2-AZOLYL)ALKYL-CHLOROACETANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BAYER AG (DE) 1982-10-27 EP disclosed