SCHEMBL39946

SCHEMBL39946

C=CCN(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.44
S1PR1 P21453 1/20 0.43
CYP1A2 P05177 1/20 0.42
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.37
KCNH2 Q12809 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9818045 1.00 ESR1 (0.44) ESR1S1PR1CYP1A2KDM4EMEN1
Ammonia Solution, Strong SCHEMBL28398668 0.97 ESR1 (0.43) ESR1S1PR1CYP1A2KDM4EMEN1
Water SCHEMBL10786878 0.97 ESR1 (0.43) ESR1S1PR1CYP1A2KDM4EMEN1
SCHEMBL3265246 0.91 ALDH1A1 (0.41) ESR1S1PR1CYP1A2KDM4EMEN1
SCHEMBL3435243 0.89 CHKA (0.41) ESR1S1PR1CYP1A2KDM4EMEN1
SCHEMBL4047348 0.87 ESR1 (0.38) ESR1S1PR1CYP1A2KDM4EMEN1
SCHEMBL9285160 0.87 CYP3A4 (0.54) ESR1S1PR1CYP1A2KDM4EMEN1
SCHEMBL4565156 0.84 ALDH1A1 (0.48) ESR1CYP1A2MEN1KMT2ATSHR
SCHEMBL12373284 0.84 ALDH1A1 (0.46) ESR1S1PR1CYP1A2KDM4EMEN1
SCHEMBL8015667 0.83 MAPT (0.44) ESR1S1PR1CYP1A2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8113 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960660-B Lubricating oil composition for gasoline engine and preparation method thereof 中国石油化工股份有限公司 2024-07-09 CN claimed
CN-115960663-B Methanol fuel engine lubricating oil composition and preparation method thereof 中国石油化工股份有限公司 2024-07-09 CN claimed
CN-115960662-B Lubricating oil composition for gas engine and preparation method thereof 中国石油化工股份有限公司 2024-07-09 CN claimed
US-20240209277-A1 DETERGENT- FREE AND LOW- ASH LUBRICATING COMPOSITION AFTON CHEMICAL CORPORATION 2024-06-27 US claimed
WO-2024137363-A1 DETERGENT-FREE AND LOW-ASH LUBRICATING COMPOSITION AFTON CHEMICAL CORPORATION (US) 2024-06-27 WO claimed
CN-116590072-B Composite additive for gear oil of wind driven generator 安徽金德润滑科技有限公司 2024-06-25 CN claimed
CN-118185689-A Lubricating oil additive and application thereof 锦州康泰润滑油添加剂有限公司 2024-06-14 CN claimed
CN-118027907-B High-temperature insulating heat conducting oil for energy storage equipment and preparation method thereof 大连天宇热能有限公司 2024-06-14 CN claimed
CN-118146854-A Lubricating oil composition for gas engine, preparation method and application 中国石油天然气股份有限公司 2024-06-07 CN claimed
CN-118006384-B Antistatic hydraulic oil 烟台广和润滑油有限公司 2024-06-07 CN claimed
EP-0523064-A1 LUBRICATING GREASE COMPOSITION. EXXON RESEARCH ENGINEERING CO (US) 1993-01-20 EP claimed
EP-0165574-B1 METHOD FOR PRODUCTION OF MALEIMIDES Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1992-08-19 EP claimed
EP-0317602-B1 ANTI-OXIDANT PRODUCTS The Lubrizol Corporation (US) 1991-10-09 EP claimed
WO-1991013955-A1 LUBRICATING GREASE COMPOSITION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1991-09-19 WO claimed
US-5037569-A Anti-oxidant products THE LUBRIZOL CORPORATION (US) 1991-08-06 US claimed
EP-0439059-A2 1-Phenylalkyl-3-phenylurea derivative Mitsubishi Chemical Corporation (JP) 1991-07-31 EP claimed
US-4769164-A Anti-oxidant products THE LUBRIZOL CORPORATION (US) 1988-09-06 US claimed
US-4690935-A Inhibition of tumor growth and metastasis with calcium channel blocker compounds WAYNE STATE UNIVERSITY (US) 1987-09-01 US claimed
US-4623734-A RING CLOSURE IMIDATION OF MALEAMIC ACID IN APROTIC SOLVENT NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1986-11-18 US claimed
EP-0165574-A2 Method for production of maleimides Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1985-12-27 EP claimed