Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.60 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239532 | 0.90 | ABCB1 (0.57) | LMNASMN1; SMN2ABCB1ABCC1CYP1A2 | |
| SCHEMBL11224497 | 0.86 | LMNA (0.60) | LMNASMN1; SMN2ABCB1CHEK1PIM1 | |
| SCHEMBL11233843 | 0.85 | SERPINE1 (0.60) | LMNASMN1; SMN2ABCB1CYP1A2CYP3A4 | |
| SCHEMBL6349404 | 0.85 | LMNA (0.81) | LMNASMN1; SMN2ABCB1CHEK1PIM1 | |
| SCHEMBL4699872 | 0.83 | CHEK1 (0.76) | LMNASMN1; SMN2ABCB1CHEK1PIM1 | |
| SCHEMBL11573780 | 0.82 | AKR1C4 (0.64) | LMNASMN1; SMN2CYP1A2CHEK1PIM1 | |
| SCHEMBL6355599 | 0.81 | LMNA (0.56) | LMNASMN1; SMN2ABCB1CHEK1PIM1 | |
| SCHEMBL6673290 | 0.80 | ABCB1 (0.55) | LMNASMN1; SMN2ABCB1ABCC1CYP1A2 | |
| SCHEMBL6673286 | 0.80 | ABCB1 (0.55) | LMNASMN1; SMN2ABCB1ABCC1CYP1A2 | |
| SCHEMBL7919608 | 0.79 | ABCB1 (0.78) | ABCB1ABCC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337270-A | ANTIALLERGENS; ANTIANAPHYLACTIC AGENTS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1982-06-29 | — | — | US | disclosed |