Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349877 | 0.88 | CHEK1 (0.66) | ALDH1A1TDP1ABL1RIN1POLB | |
| SCHEMBL6353430 | 0.86 | MAPT (0.57) | SMN1; SMN2ALDH1A1ABCB1POLBALB | |
| SCHEMBL6352362 | 0.86 | CHEK1 (0.54) | LMNAALDH1A1TDP1ABL1RIN1 | |
| SCHEMBL6359657 | 0.83 | MAPT (0.70) | SMN1; SMN2ALDH1A1TDP1POLBALB | |
| SCHEMBL6357377 | 0.83 | SMN1; SMN2 (0.52) | LMNASMN1; SMN2ALDH1A1ABL1RIN1 | |
| SCHEMBL6351826 | 0.83 | CHEK1 (0.53) | LMNAALDH1A1TDP1ABL1RIN1 | |
| SCHEMBL11224497 | 0.83 | LMNA (0.60) | LMNASMN1; SMN2ALDH1A1ABCB1TDP1 | |
| SCHEMBL11224871 | 0.81 | LMNA (0.62) | LMNASMN1; SMN2ALDH1A1ABCB1TDP1 | |
| SCHEMBL6349404 | 0.81 | LMNA (0.81) | LMNASMN1; SMN2ALDH1A1ABCB1TDP1 | |
| SCHEMBL11233843 | 0.81 | SERPINE1 (0.60) | LMNASMN1; SMN2ALDH1A1ABCB1CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | LMNA 4552/4885SMN1; SMN2 3015/4885ALDH1A1 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.