Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 8/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.52 |
| ▸ | PLAU | P00749 | 2/20 | 0.39 |
| ▸ | PLAUR | Q03405 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885174 | 0.79 | DPP7 (0.46) | DPP7DPP8DPP9PLAUPLAUR | |
| SCHEMBL3277465 | 0.76 | DPP7 (0.45) | DPP7DPP8DPP9DPP4FAP | |
| SCHEMBL5552493 | 0.76 | DPP8 (0.43) | DPP7DPP8DPP9PLAUPLAUR | |
| SCHEMBL649164 | 0.76 | DPP8 (0.43) | DPP7DPP8DPP9PLAUPLAUR | |
| SCHEMBL10889358 | 0.76 | DPP7 (0.43) | DPP7DPP8DPP9PLAUPLAUR | |
| SCHEMBL11197546 | 0.75 | DPP7 (0.44) | DPP7DPP8DPP9DPP4FAP | |
| Water SCHEMBL3369508 | 0.75 | DPP7 (0.42) | DPP7DPP8DPP9PLAUPLAUR | |
| SCHEMBL7759076 | 0.72 | OPRK1 (0.41) | DPP7DPP8DPP9DPP4MMP2 | |
| SCHEMBL10883512 | 0.72 | DPP7 (0.39) | DPP7DPP8DPP9DPP4MMP2 | |
| SCHEMBL7758752 | 0.71 | DPP7 (0.40) | DPP7DPP8DPP9DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079522-A1 | N-Carboxymethyl(amidino)lysyl-proline antihypertensive agents | MERCK & CO. INC. (US) | 1983-05-25 | — | — | EP | disclosed |