Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA6 | P23280 | 3/20 | 0.39 |
| ▸ | CA7 | P43166 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386042 | 1.00 | KDM4E (0.50) | KDM4ECA12CA6CA7CA9 | |
| SCHEMBL11235646 | 0.96 | KDM4E (0.53) | KDM4EALDH1A1HTTKMT2AADRB2 | |
| SCHEMBL16948555 | 0.91 | KDM4E (0.59) | KDM4EHTTKMT2AMEN1ADRB2 | |
| SCHEMBL11387212 | 0.89 | KDM4E (0.50) | KDM4ECA12CA6CA7CA9 | |
| SCHEMBL14726523 | 0.86 | KDM4E (0.47) | KDM4ECA12CA6CA7CA9 | |
| SCHEMBL14198102 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1KMT2AADRB2ADRB1 | |
| SCHEMBL17188506 | 0.84 | KDM4E (0.48) | KDM4ETDP1ALDH1A1HTTKMT2A | |
| SCHEMBL11231807 | 0.84 | KDM4E (0.52) | KDM4ETDP1ALDH1A1HTTKMT2A | |
| SCHEMBL13343920 | 0.81 | KDM4E (0.44) | KDM4ECA12CA6CA7CA9 | |
| SCHEMBL11232438 | 0.81 | HTT (0.54) | KDM4EALDH1A1ALOX15HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315846-A | FUNGICIDES | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1982-02-16 | — | — | US | disclosed |