Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11386042 | 0.96 | KDM4E (0.50) | KDM4EHTTANPEPALDH1A1KMT2A | |
| SCHEMBL11225463 | 0.96 | KDM4E (0.50) | KDM4EHTTANPEPALDH1A1KMT2A | |
| SCHEMBL11387212 | 0.93 | KDM4E (0.50) | KDM4EHTTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL14726523 | 0.90 | KDM4E (0.47) | KDM4EHTTANPEPALDH1A1KMT2A | |
| SCHEMBL14198102 | 0.88 | KDM4E (0.57) | KDM4EALDH1A1KMT2ASMN1; SMN2ADRB2 | |
| SCHEMBL11231807 | 0.87 | KDM4E (0.52) | KDM4EHTTANPEPALDH1A1KMT2A | |
| SCHEMBL16948555 | 0.86 | KDM4E (0.59) | KDM4EHTTKMT2AADRB2ADRB1 | |
| SCHEMBL11232438 | 0.84 | HTT (0.54) | KDM4EHTTALDH1A1KMT2A | |
| SCHEMBL11023778 | 0.82 | HTT (0.62) | KDM4EHTT | |
| SCHEMBL23742102 | 0.81 | KDM4E (0.46) | KDM4EHTTANPEPALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315846-A | FUNGICIDES | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1982-02-16 | — | — | US | disclosed |
| EP-0037861-A1 | Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi | TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) | 1981-10-21 | — | — | EP | disclosed |