Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | F13A1 | P00488 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA6 | P23280 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | THPO | P40225 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11387212 | 0.93 | KDM4E (0.50) | KDM4ECA12F13A1CA2CYP1A2 | |
| SCHEMBL11235646 | 0.90 | KDM4E (0.53) | KDM4EHTTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL14198102 | 0.89 | KDM4E (0.57) | KDM4EPKMSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11386042 | 0.86 | KDM4E (0.50) | KDM4ECA12CA2ALOX15CA4 | |
| SCHEMBL11225463 | 0.86 | KDM4E (0.50) | KDM4ECA12CA2ALOX15CA4 | |
| SCHEMBL13600228 | 0.84 | KDM4E (0.44) | KDM4ECA12F13A1CA2CYP1A2 | |
| SCHEMBL9364333 | 0.80 | CA12 (0.44) | CA12F13A1CA2CYP1A2ALOX15 | |
| SCHEMBL16948555 | 0.80 | KDM4E (0.59) | KDM4EHTTKMT2AMEN1 | |
| SCHEMBL9325021 | 0.80 | CA12 (0.52) | CA12F13A1CA2CYP1A2ALOX15 | |
| SCHEMBL12761111 | 0.79 | HTT (0.51) | KDM4ECYP1A2ALOX15HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130048559-A1 | Method of Preparing a Substrate for Immobilization of Functional Substances Thereon and the Substrate Obtained Therefrom | TEMASEK POLYTECHNIC (SG) | 2013-02-28 | — | — | US | disclosed |